Scientific work of the Department of Internal and occupational diseases

Areas of research. Research work of the department is devoted to the issues of industrial cardiology, study of the effect of industrial aerosol and vibration on the body on machinery manufacturing workers. The peculiarities of the course of cardiovascular pathology in different professional groups are studied, the relationship of occupational diseases with hypertension, atherosclerosis, coronary heart disease.

The main scientific achievements of the department. In recent years, the department has been conducting research work on the program “Fighting hypertension in the organized population (industry) of Kharkiv”. The main scientific achievements of the department. The work made it possible to actively identify people suffering from hypertension, treat them and assess the possibility of reducing morbidity and mortality primarily from cardiovascular and cerebrovascular diseases. A system of treatment of arterial hypertension in industrial workers has been developed, the influence of occupational factors in the occurrence of arterial hypertension has been determined.

According to the results of research work of the department 2 doctoral and 4 candidate dissertations in the period 2016-2021 were defended. Scientific achievements are covered in many articles in professional journals of Ukraine and the world, including 21 articles for 2016-2021 in publications included in the scientific databases SCOPUS / Web of Science.

The results of the scientific work of the department were presented at the national congresses of cardiologists of Ukraine, the congress of pulmonologists of Ukraine, other professional forums of Ukraine. Scientific achievements were widely reported abroad at the following international congresses: European Respiratory Society (Paris, France), European Congress Heart Failure 2019: 6th World Congress on Acute Heart Failure (Athens, Greece); European Atherosclerosis Society Congress (Maastricht, The Netherlands), 29 European meeting on hypertension and cardiovascular protection (Milan, Italy); Congresses of the Korean Society of Cardiology (Seoul, Republic of Korea), at scientific and practical conferences of various countries, including Tajikistan, Azerbaijan, Uzbekistan, etc.

The concept of vibration disease as a membrane pathology is formulated, which consists, in particular, in the violation of transmembrane calcium metabolism, disintegration of erythrocyte cytoskeleton proteins with changes in the properties of the membrane spectrin-actin complex. This became the basis for the development of pathogenetic therapy with the use of slow calcium channel blockers in the treatment of this category of patients.